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Monday, June 16, 2025

The oldest organ in your mouth isn’t what you suppose


3.5 billion years of evolution gave you a built-in defend towards cavities and gum illness.

Right here’s why it not works.

Biofilms are sometimes called the “pores and skin” of the tooth, a easy and ubiquitous layer that adheres to exhausting surfaces like tooth. Nevertheless, this description fails to seize the true essence of biofilms as basic organic techniques. 

Biofilms are far older than the human species, originating within the earliest levels of life on Earth. They characterize one of many first types of organized life and have developed over billions of years to function vital survival mechanisms for microorganisms. 

But, in as we speak’s world, the biofilm faces a profound mismatch with trendy environmental circumstances, resulting in a bunch of oral well being points. Understanding biofilms as primordial organ techniques that developed below very completely different circumstances can make clear how we would higher take care of them in as we speak’s world.

The Historical Origins of Biofilms

  • Biofilms are among the many earliest life types on Earth, with fossilized microbial mats present in stromatolites courting again 3.5 billion years. 
  • These early biofilms had been constructed by prokaryotic organisms like cyanobacteria—life types that thrived in low-oxygen, excessive environments. 
  • The formation of biofilms allowed these microorganisms to defend themselves from dangerous ultraviolet radiation, stop desiccation (drying out), and share vitamins effectively. 
  • Biofilms additionally offered a mechanism for genetic change, enhancing the adaptability of those youth types.

Magnesium (right here’s the hyperlink to the one I take) performed an important function in enabling these early organic techniques to perform:

  • It prompts enzymes, transfers vitality (through ATP), and stabilizes DNA and RNA.
  • Alongside iron and phosphorus, magnesium made life attainable.

Biofilms weren’t simply shields—they had been the stepping stones to multicellular life. Their construction enabled cooperation, communication, and early complexity.

Biofilms and the Oral Microbiome

In people, the oral biofilm is an important part of our oral microbiome. It serves as a bodily defend for the tooth, offering safety towards dangerous micro organism that might trigger decay or gum illness. 

This biofilm isn’t just a passive layer; it has energetic features that promote oral well being. It comprises antimicrobial brokers and hosts immune responses, together with antibodies, to assist defend towards pathogens. 

The biofilm additionally helps regulate pH ranges within the mouth and assists within the remineralization of the tooth by transferring calcium from saliva to areas of the tooth which have been demineralized.

Biofilm is dynamic. Micro organism throughout the biofilm talk with one another by way of quorum sensing, a course of that permits them to coordinate their actions, regulate to altering environmental circumstances, and keep a wholesome stability. The biofilm thus acts as a regulator of the oral ecosystem, making certain that useful micro organism thrive whereas dangerous ones are stored at bay.

The Mismatch with Fashionable Life

Regardless of their evolutionary success, biofilms now face challenges they had been by no means designed for:

  • Dietary Adjustments: Fashionable diets are wealthy in sugars and fermentable carbs. Dangerous micro organism thrive and create acid, inflicting enamel loss.
  • Processed Meals: Excessive in refined sugars, these promote the overgrowth of damaging micro organism.
  • Dry Mouth: Brought on by dehydration, medicines, and mouth respiration. This lowers pH and favors dangerous strains.
  • Frequent Snacking: Fixed meals publicity prevents biofilm restoration.
  • Oral Care Merchandise:
    For many years, oral care has targeted on sterilization. However the oral microbiome is a dwelling organ system—it wants stability, not eradication. This is the reason I co-founded Fygg (Feed Your Good Guys). Alcohol, triclosan, detergents, emulsifiers, and even “pure” important oils disrupt the ecosystem we rely on. In attempting to wash our mouths, we’ve created microbial sabotage.

This mismatch between the biofilm’s evolutionary design and trendy dwelling circumstances results in a bunch of oral well being issues, together with cavities, gum illness, and different systemic results.

Mismatch Illnesses: What Occurs When the Biofilm Can’t Adapt

  • Cavities (Dental Caries): Sugar feeds acid-producing micro organism that break down enamel.
  • Gum Illness (Gingivitis and Periodontitis): Microbial imbalance causes irritation and an infection.
  • Rebound from Harsh Merchandise: Overuse of antibacterial mouthwash can destroy good micro organism—inflicting imbalance.
  • Dry Mouth and pH Points: A dry, acidic setting feeds pathogens.
  • Systemic Results: Oral pathogens could enter the bloodstream and contribute to illnesses like Alzheimer’s and coronary heart illness.

Supporting the Biofilm: The Path Ahead

As a substitute of specializing in killing the biofilm with harsh chemical compounds or aggressive brushing, we must always goal to help and nourish it. Biofilms live techniques which have developed over billions of years, and with the fitting circumstances, they will proceed to guard the tooth and keep oral well being.

Listed below are some methods for supporting the biofilm:

  • Mild Brushing: Brushing shouldn’t be about scrubbing away the biofilm. As a substitute, it ought to be targeted on gently disorganizing the micro organism to reset the stability. Utilizing a soft-bristled toothbrush and non-abrasive toothpaste ensures that the biofilm just isn’t disrupted too aggressively.
  • Correct Hydration: Saliva performs a vital function in sustaining the biofilm. Consuming loads of water and avoiding dry mouth helps preserve the biofilm hydrated and functioning correctly.
  • Wholesome Weight-reduction plan: A weight loss program low in processed sugars and excessive in vitamins and minerals (like magnesium) and electrolytes helps help the wholesome micro organism within the biofilm, permitting it to thrive and shield the tooth.
  • Oil Pulling: This apply includes swishing oil, usually coconut or sesame, within the mouth to assist cleanse and keep the biofilm. In contrast to abrasive brushing, oil pulling doesn’t scrub or take away the biofilm however helps to skinny it gently. By doing so, it encourages a stability within the oral microbiome, permitting useful micro organism to thrive whereas stopping the overgrowth of dangerous micro organism. It’s a easy, pure strategy to help oral well being with out disrupting the biofilm’s protecting function.
  • Use Nourishing Oral Care Merchandise: It’s important to decide on merchandise that nourish the oral microbiome. The appropriate merchandise, together with non-abrasive toothpaste and important oil-free toothpaste, help the biofilm’s well being by sustaining a balanced, thriving setting for the useful micro organism. These merchandise assist reinforce the biofilm’s protecting function moderately than stripping it away.

Biofilms are excess of a easy layer on the tooth—they’re historic techniques which have performed a vital function within the survival of life on Earth. The biofilm in our mouths is a dwelling organ system that developed to guard us from pathogens and keep oral well being. Nevertheless, the trendy setting has created a mismatch between the biofilm’s evolutionary design and the stresses it now faces.

The biofilm is there for a motive—to guard and stability your mouth. Deal with it with respect, and it’ll proceed to do its job.

-Dr. B

P.S. I did a model new podcast interview final week. Give it a pay attention and let me know what you suppose!

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